Action of Administered Ciliary Neurotrophic Factor on the Mouse Dorsal Vagal Complex
نویسندگان
چکیده
منابع مشابه
Action of Administered Ciliary Neurotrophic Factor on the Mouse Dorsal Vagal Complex
Ciliary neurotrophic factor (CNTF) induces weight loss in obese rodents and humans through activation of the hypothalamic Jak-STAT (Janus kinase-signal transducer and activator of transcription) signaling pathway. Here, we tested the hypothesis that CNTF also affects the brainstem centers involved in feeding and energy balance regulation. To this end, wild-type and leptin-deficient (ob/ob and d...
متن کاملBrain-derived neurotrophic factor plays a role as an anorexigenic factor in the dorsal vagal complex.
Brain-derived neurotrophic factor (BDNF) has recently been implicated as an anorexigenic factor in the central control of food intake. Previous studies focused on the hypothalamus as a probable site of action for this neurotrophin. It was demonstrated that BDNF is an important downstream effector of melanocortin signaling in the ventromedial hypothalamus. In this study, we addressed whether BDN...
متن کاملThe trophic effect of ciliary neurotrophic factor on injured masseter muscle in rat
Objective(s): Occlusal trauma is one of the most common forms of oral biting dysfunction. Long-term occlusal trauma could weaken the stomatognathic system; especially damage one’s masticatory muscle. Through using the rat model, this study investigated the trophic effect of ciliary neurotrophic factor (CNTF) on injured masseter muscle. Materials and Methods: Male Wistar rats (n=36) were random...
متن کاملthe trophic effect of ciliary neurotrophic factor on injured masseter muscle in rat
objective(s): occlusal trauma is one of the most common forms of oral biting dysfunction. long-term occlusal trauma could weaken the stomatognathic system; especially damage one’s masticatory muscle. through using the rat model, this study investigated the trophic effect of ciliary neurotrophic factor (cntf) on injured masseter muscle. materials and methods: male wistar rats (n=36) were randoml...
متن کاملAction of brain-derived neurotrophic factor on function and morphology of visual cortical neurons
Brain-derived neurotrophic factor (BDNF) is known to play a role in experience-dependent plasticity of the developing visual cortex. For example, BDNF acutely enhances long-term potentiation and blocks long-term depression in the visual cortex of young rats. Such acute actions of BDNF suggested to be mediated mainly through presynaptic mechanisms. A chronic application of BDNF to the visual cor...
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ژورنال
عنوان ژورنال: Frontiers in Neuroscience
سال: 2016
ISSN: 1662-453X
DOI: 10.3389/fnins.2016.00289